Research Article

Spectrophotometric Determination of Some Non-Sedating Antihistamines Using Erythrosine B

Table 3

Accuracy and precision of the developed spectrophotometric method.

Authentic drugConcentration (μg/mL)RSD %Accuracy* %
Inter-day precisionIntra-day precision

CTZ2 0.69 0.85 98.17
4 1.31 0.59 101.76
60.85 0.85100.99

EBS2 1.22 1.15 99.20
4 1.27 0.76 98.45
6 0.260.3899.46

FXD2 1.59 1.07 99.80
4 0.73 0.65 99.84
6 0.530.51101.43

KET 2 0.98 0.59 99.33
4 0.73 0.71 100.24
6 0.370.28101.90

LOR2 1.64 1.29 99.87
4 0.62 0.45 99.66
60.330.2299.83

Average of six replicates.