Spectrophotometric Determination of Some Non-Sedating Antihistamines Using Erythrosine B

Table 5

Assay of tablets of investigated non-sedating antihistamines by the developed method and reported methods.

Authentic drug	Dosage form	% Recovery^a ± SD		t-value^b	F-value^b
		Proposed method	Reported method
CTZ	Epirizine tablets	99.97±0.65	99.74±1.45^∗	0.36	4.94
EBS	Evastine tablets	98.24±1.12	98.07±1.49^∗∗	0.22	1.77
FXD	Allerfen tablets	99.39±0.90	99.25±1.38^∗	0.22	2.36
KET	Zaditen tablets	98.52±1.07	98.18±1.07^∗∗∗	0.55	1.00
LOR	Mosedine tablets	100.31±1.25	99.20±0.97^∗	1.72	1.66

aAverage of six determinations ± standard deviation.
^bTheoretical values at 95% confidence limit; t = 2.228, F = 5.053.
*Reference [22].
**Reference [24].
***Reference [21].