Spectrophotometric Determination of Some Non-Sedating Antihistamines Using Erythrosine B

Table 6

Assay of tablets by standard addition method.

Authentic drug	Dosage form	Claimed taken (µg/mL)	Authentic added (µg/mL)	Found concentration (µg/mL)	% Recovery ± SD*	C.V
CTZ	Epirizine tablets		2	1.996	99.82±1.18	1.18
		2	3	2.995	99.83±1.09	1.09
			4	3.999	99.97±0.65	0.65
EBS	Evastine tablets		2	1.965	98.24±1.12	1.14
		2	3	2.996	99.87±1.53	1.53
			4	3.977	99.42±1.57	1.58
FXD	Allerfen tablets		2	2.005	100.23±1.31	1.31
		2	3	3.004	100.14±1.18	1.18
			4	3.976	99.39±0.90	0.90
KET	Zaditen tablets		2	1.967	98.36±1.41	1.44
		2	3	2.956	98.52±1.07	1.09
			4	3.988	99.69±1.44	1.45
LOR	Mosedine tablets		2	2.026	101.28±1.65	1.63
		2	3	3.009	100.31±1.25	1.25
			4	4.038	100.96±1.12	1.11

∗Average of six replicates.