Research Article

Amelogenin Peptide Extract Increases Differentiation and Angiogenic and Local Factor Production and Inhibits Apoptosis in Human Osteoblasts

Figure 2

Effect of rhAmelogenin and Fraction C on DNA content and osteoblast phenotype of MG63 cells. MG63 cells were grown to confluence and then treated with 0 μg/mL or 0.01 μg/mL–100 μg/mL rhAmelogenin or Fraction C for 24 hours. DNA content (a) and alkaline phosphatase-specific activity (b) were measured in the cell lysate, and osteocalcin (c) and osteoprotegerin (d) measured in the conditioned media. * , versus 0 μg/mL; , versus 1 μg/mL.
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