Research Article

CD133 Staining Detects Acute Kidney Injury and Differentiates Clear Cell Papillary Renal Cell Carcinoma from Other Renal Tumors

Figure 5

CD133 expression in clear cell papillary renal cell carcinoma (RCC). CD133 stained negatively in a clear cell RCC (a) but showed diffuse cellular membrane expression of CD133 (monoclonal) in clear cell papillary RCC (b). The clear cell papillary RCC cells also demonstrated coexpression of CD133 (polyclonal) and OCT3/4 (monoclonal), another stem cell marker in the same tumor cells (c). CD133 was expressed in clear cell papillary RCC and regenerative tubules at the peritumoral area (d) (magnification ×400, (a)–(c); ×200, (d)).
353598.fig.005a
(a) Negative CD133 in clear cell RCC
353598.fig.005b
(b) +CD133 in CCP-RCC
353598.fig.005c
(c) + CD133 and OCT3/4 in CCP-RCC
353598.fig.005d
(d) CD133 in peritumoral tubules (arrows)