Review Article

Postoperative Complications following Nodal Dissection and Their Association with Melanoma Recurrence

Table 2

Nodal characteristics, recurrence and survival.

Characteristics Inguinal dissection ( )Axillary dissection ( ) value

Sentinel node
 Macrometastasis18 (28.6%)13 (31.7%)0.772
 Micrometastasis 44 (69.8%)22 (53.7%)0.106
 Immunohistochemical1 (1.6%)6 (14.4%)0.01
Total nodes (mean ± SD)11.45 (±4.9)19.76 (±10.8)<0.001
Median of total nodes 1118
Positive nodes (mean ± SD)1.93 (±3.25)2.12 (±3.27)0.722
Median of positive nodes 11
% of positive nodes (mean ± SD)16.84 (±24.56)14.37 (±24.87)0.615
Recurrence rate 53 (84.1%)26 (63.4%)0.016
Mean time to recurrence (months)28.9 (±24)34 (±27.7)0.206
Site of recurrence
 Local or in transit13 (20.6%)6 (14.6%)0.887
 Nodal 16 (25.4%)7 (17.5%)0.764
 Distant 42 (66.7%)22 (53.7%)0.567
Mortality 43 (68.3%)20 (48.8%)0.047