Research Article

The P25 Ookinete Surface Proteins: Homology Modeling and Phylogenetic Relationships

Figure 2

(a) Weblogo representation for the modeled 8 sequences of P25 family of ookinete surface antigens. Each logo consists of stacks of symbols, one stack for each position in the sequence. The overall height of the stack indicates the sequence conservation at that position, while the height of symbols within the stack indicates the relative frequency of each amino acid. Negatively charged (D and E), positively charged (K and R), and cysteine (C) residues are shown in red, blue, and yellow colors, respectively, whereas the rest are in black color. Conservation of cysteine residues in all the four EGF domains is well represented by the logos above. (b) Represents the root mean square deviation of the eight members of P25 family when compared to template Pvs25 protein (http://www.rcsb.org/pdb/explore/explore.do?structureId=1z27).
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(a)
391018.fig.002b
(b)