Radical Cystectomy after BCG Immunotherapy for High-Risk Nonmuscle-Invasive Bladder Cancer in Patients with Previous Prostate Radiotherapy

Table 1

Demographics of patients treated with radical cystectomy for BCG failure stratified by previous prostate radiotherapy exposure.

	Group 1 (RT)	Group 2 (RP)	Group 3 (no PC/RT)	P-value
No. of patients	12	6	35
Mean age	72.9 ± 4.69	66.9 ± 5.18	64.2 ± 10.4	0.0065
Clinical stage				0.47
CIS	5 (42)	1 (17)	8 (23)
Ta	1 (8)	1 (17)	4 (11)
T1	6 (50)	4 (66)	23 (66)
Any CIS features preop	5 (42)	2 (33)	21 (60)	0.33
Diversion type
Ileal conduit	8 (66)	1 (17)	13 (22)	0.09
Continent diversion	4 (33)	5 (83)	22 (63)
Orthotopic neobladder	0	5 (83)	17 (49)
Indiana pouch	4 (33)	0	5 (14)
Estimated blood loss (mL)	683 ± 326	640 ± 169	789 ± 522	0.65
Intraoperative complication	1 (8)	0	1 (3)	0.61
Transfusion	1 (8)	0	9 (26)	0.19
Time to RC from PC diagnosis (years)	6.2 ± 4.3	5.5 ± 2.0		0.68

Numbers represent mean ± SD or no. (%) as appropriate.
RC: radical cystectomy.