Circulating CCL5 Levels in Patients with Breast Cancer: Is There a Correlation with Lymph Node Metastasis?

Table 3

(a) Association between serum CCL5 levels (ng/mL) and tumour characteristics. (b) Pairwise comparison between serum CCL5 levels (ng/mL) and pT.

(a)

Variable	Statistics
	𝑁	Mean ± SD	Median	Range	𝑃 value
CCL5 serum
pN	149	66,83 ± 20,89	64,37	19,72–145,36
0	78	64,40 ± 22,02	60,91	31,89–145,36	0.098
1	39	68,90 ± 17,97	72,31	30,69–104,37
2/3	16	67,49 ± 17,09	66,31	32,45–102,75
CCL5 serum
pT	149	66,83 ± 20,89	64,37	19,72–145,36
1	51	60,23 ± 19,24	59,77	30,69–121,86	0.009
2	70	67,02 ± 16,73	66,34	38,94–120,93
3/4	10	82,40 ± 28,93	76,17	45,27–145,36
CCL5 serum
LVI	149	66,83 ± 20,89	64,37	19,72–145,36
No	101	66,98 ± 20,20	64,27	3189–145,36	0.408
Yes	38	63,02 ± 19,54	63,41	19,72–104,19
CCL5 serum
Multifocal	149	66,83 ± 20,89	64,37	19,72–145,36
No	120	67,46 ± 21,75	64,32	19,72–145,36	0.319
Yes	26	61,68 ± 15,19	63,87	33,97–87,83

𝑃 values are based on a Kruskal Wallis test (no. of levels > 2).
𝑃 values of pairwise comparisons are shown in next table.
Min: the lowest value, max: the highest value, Q1: percentile 25, Q3: percentile 75, SD: standard deviation.

(b)

Variable	pT (3cat.)		𝑃 values
			Raw	Bonferroni
CCL5 serum	—	—	0.009	—
	1	2	0.027	0.082
		3/4	0.013	0.039
	2	3/4	0.077	0.231

𝑃 value in bold refers to the result of the Kruskal Wallis test.
Mann-Whitney 𝑈 tests are used for pairwise comparisons. Raw 𝑃 values as well as 𝑃 values corrected for multiple testing are given.