Modulation of Vitamin D Status and Dietary Calcium Affects Bone Mineral Density and Mineral Metabolism in Göttingen Minipigs

Figure 3

Effects of calcium and vitamin D deficiency [CaD(−); dotted line] on plasma concentrations of 25-dihydroxyvitamin D [25(OH)D], (a), 1,25-dihydroxyvitamin D [1,25(OH)₂D], (b), and parathyroid hormone (PTH, (c)) compared with a control group (C; solid line). Values are changes from baseline 𝑡0, with baseline values assigned to zero. Means and SEM, 𝑛=8--10. For baseline values see Table 1. Significantly different from controls at a given time: ^[a]𝑃≤0.1; ^a𝑃≤0.05; ^b𝑃≤0.01; ^c𝑃≤0.001. Significantly different from baseline: ^[x]𝑃≤0.1; ^x𝑃≤0.05; ^y𝑃≤0.01; ^z𝑃≤0.001.

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(b)

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