The Surgical Treatment for Portal Hypertension: A Systematic Review and Meta-Analysis

Table 1

Summary of included RCTs.

Study	Year	Country	Sample size	Follow-up time	Outcomes
Wang et al. [14]	2002	China	30	1 year	PVF, FPP, HTF, R15 ICG
Xu et al. [15]	1997	China	26	Unclear	PHG
Vons et al. [16]	1996	France	15	6 months	Long-term hemodynamics
Borgonovo et al. [17]	1996	Italy	54	Unclear	Encephalopathy, rebleeding, survival, ascites, hepatocellular carcinoma
Xu et al. [18]	2003	China	66	7 years	Hemodynamics
Zhao et al. [19]	2009	China	78	6 months–5 years	Hemodynamics
Gao et al. [20]	2002	China	220	1–5 years	Hemodynamics
Wang et al. [21]	2000	China	64	6 months–20 years	Hemodynamics
de Cleva et al. [22]	2007	Brazil	36	6–84 months	Hemodynamics
Strauss et al. [23]	1999	Brazil	73	5–10 years	Size of gastroesophageal varices
da Silva et al. [24–26]	1986	France	94	>5 years	Encephalopathy, rebleeding, failure, mortality
Grace et al. [27]	1988	Boston	81	Mean of 3.5 years	Late mortality, cumulative survival, hemorrhage from varices, encephalopathy
Warren and whithead [28]	1986	USA	55	11 years	Rebleeding, hepatic cell function, quality of life
Conn et al. [10]	1981	USA	53	54 months	Encephalopathy, rebleeding, mortality
Fischer et al. [29]	1981	USA	42	60 months	Encephalopathy, rebleeding, mortality
Orozco et al. [30]	1994	USA	55	>16 months	Encephalopathy, mortality, hepatic portal perfusion, hepatic function

PVF: portal vein pressure; FPP: free portal pressure; PHG: portal hypertensive gastropathy; HTF: total hepatic flow; R15: ICG indocyanine green retention rate at 15 min.