512527.fig.002a
(a)
512527.fig.002b
(b)
512527.fig.002c
(c)
512527.fig.002d
(d)
Figure 2: Expression of IgM, IgD, CD23, and CD27 surface molecules identifying 4 consecutive steps of B cell mauration in patients with CVID. Number of: (a) IgM+ IgD+ CD23+ CD27− (Naïve B cells), (b) IgM+ IgD− CD23− CD27−, (c) IgM− IgD− CD23− CD27−, and (d) IgM− IgD− CD23− CD27+ (switched memory B cells) in healthy controls (dark grey bar) and in CVID patients (light grey bar). Number of cells are reported on vertical axis.