529463.fig.004a
(a)
529463.fig.004b
(b)
Figure 4: MEG in autism research. (a) The ECD locations for responses to images of human faces at about 145 ms after stimulus onset in a typically developing subject and an individual with ASD (circle indicates the volume conductor sphere). These images illustrate locations in the right posterior cortices of the generators, where, on average, dipole locations are more lateral in TD compared to ASD. (b) Grand root-mean-square signals following face images. The curves have been obtained by summation over all participants within a participant group (blue, boys with ASD; red, typically developing boys; and stimulus onset at 0) and channels. Even in middle childhood, the neural mechanisms underlying face processing are less specialized than in adults (inset) with greater early activation of posterior occipital cortices (I, II) and less specific activation of ventral occipitotemporal cortex (III), particularly in boys with ASD.