Clinical Study

Radiographic Parameters in Predicting Outcome of Patients with Hepatocellular Carcinoma Treated with Yttrium-90 Microsphere Radioembolization

Table 1

Response to treatment graded by Morphology, Attenuation, Size, and Structure (MASS) criteria*.

Response categoryMASS criteria description

Favorable responseNo new lesions and either of the following:
(1) decrease in tumor size ≥20%;
(2) ≥1 predominantly solid enhancing lesion with marked central necrosis or marked decreased attenuation

Indeterminate responseDoes not fit criteria for favorable or unfavorable response

Unfavorable responseEither of the following:
(1) increase in tumor size ≥20% without marked central necrosis or marked decreased attenuation;
(2) new metastases, marked central fill-in, or new enhancement of a previously homogeneously hypoattenuating, nonenhancing mass

Described by Smith et al. [23].