Clinical Study

Retrospective Analysis of Efficacy and Safety of Tocilizumab Treatment in Patients with Severe Systemic-Onset Juvenile Idiopathic Arthritis Followed for 12 Months

Table 2

Characteristics of previous therapy in patients with sJIA at the moment of enrollment in the study.

DrugDose
(median (25; 75))
Number of children

Methotrexate, mg/m2/week19 (15; 24)25
Methotrexate, mg/m2/week +17 (15; 23)
Cyclosporine, mg/kg/day4 (4; 4)47
Methotrexate, mg/m2/week +12
Mycophenolate mofetil, mg/day10001
Methotrexate, mg/m2/week +15
Leflunomide202
Prednisolone, mg/day9.5 (6.5; 12)44
NSAIDs75
Rituximab 22
Infliximab 17
Adalimumab 6
Etanercept 2
Number of biologics
 3 products5
 2 products10
 1 product14