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International Scholarly Research Notices
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International Scholarly Research Notices
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2013
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Article
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Tab 5
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Clinical Study
Retrospective Analysis of Efficacy and Safety of Tocilizumab Treatment in Patients with Severe Systemic-Onset Juvenile Idiopathic Arthritis Followed for 12 Months
Table 5
Adverse events in patients treated with tocilizumab.
Adverse events
Patients,
(%)
Laboratory abnormalities:
Neutropenia
30 (40%)
Thrombocytopenia
2 (2%)
Elevation of alkaline phosphatase
1 (1%)
Elevation of aminotransferases
15 (20%)
Infections:
Gastroenteritis
11 (14%)
Nasopharyngitis
72 (96%)
Upper respiratory tract infections
56 (74%)
Cellulitis
3 (4%)
Herpes outbreak
6 (8%)
Acute focal pneumonia
3 (4%)
Number of infectious AEs per patient-year
2.2
Macrophage activation syndrome
1 (1%)