Cell Transplantation and “Stem Cell Therapy” in the Treatment of Myopathies: Many Promises in Mice, Few Realities in Humans

Figure 5

Schematic representation of the location of the satellite cell (yellow) in its niche between the sarcolemma and the basal lamina (a). (b) shows a satellite cell (between arrowheads) of a nonhuman primate observed by electron microscopy. Blue arrowheads indicate the basal lamina, and red arrowheads indicate the thin space between the sarcolemma and the satellite cell. The dense nucleus with clumped chromatin and the little undifferentiated cytoplasm are typical of satellite cells. Scale bar = 1 μm.