Review Article
Pharmacotherapy of Chronic Obstructive Pulmonary Disease: A Clinical Review
Table 4
Mode of administration, chemical structure, lipophilicity (
), and half time (
) of glucocorticosteroids.
| Compound | Mode of administration | Chemical structure | | |
| Fluticasone propionate | Inhalation (MDI, DPI) | | 3.4 | 10 hours | Budesonide | Inhalation (DPI, solution) | | 1.9 | 2.0–3.6 hours | Beclomethasone | Inhalation (MDI, DPI, and solution) | | 1.3 | 2.8 hours | Flunisolide | Inhalation (MDI, DPI, and solution) | | 1.1 | 1.8 hours | Mometasone furoate | Inhalation (MDI, DPI, and solution) | | 2.1 | 5.8 hours | Triamcinolone | Inhalation (MDI, DPI, and solution) | | 0.2 | 88 minutes |
|
|
MDI: metered-dose inhaler, DPI: dry power inhaler.
|