Research Article

Protective Effects of Guava Pulp on Cholestatic Liver Injury

Figure 1

Effect of guava pulp on bilirubin and alanine aminotransferase (ALT) levels. (a) The guava tree. The guava tree is the apple guava (Psidium guajava) tree. It is native to Mexico. (b) Guava fruit. Guava fruit is oval, with a soft and sweet taste. As guava becomes mature, the skin changes into yellow from green, with deep pink fresh (“red” guavas) and the seeds in the central pulp of variable number and hardness. (c) Dose response of GP on serum ALT level in the LMBDL. The mean ± standard errors are , , , and in the groups of 0, 10, 15, and 20 (mL/kg/per each feeding). 10 mL/kg/per each feeding versus 15 and 20 mL/kg/per each feeding, respectively. (d) Bilirubin levels in the ligated and unligated lobes. Liver homogenate was extracted from the ligated (left and median) and unligated (right and caudate) lobes to assess changes of bilirubin level. , the ligated lobes at day 1, 7 and 28 versus the unligated lobes at days 1, 7, and 28, respectively. (e) Serum bilirubin level. , the LMBDL+GP groups at days 1, 7, and 28 versus the LMBDL groups at 1, 7, and 28, respectively. (f) Serum alanine aminotransferase (ALT) levels. , the LMBDL+GP groups at days 1, 7, and 28 versus the LMBDL groups at 1, 7, and 28, respectively.
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