Sex-Related Difference in Nitric Oxide Metabolites Levels after Nephroprotectant Supplementation Administration against Cisplatin-Induced Nephrotoxicity in Wistar Rat Model: The Role of Vitamin E, Erythropoietin, or N-Acetylcysteine

Table 1

Effect of CP on serum NO_𝑥, nitrate, and nitrite levels in male and female rats. The data was compared between negative and positive control groups using Student’s 𝑡-test.

Factors		NO𝑥 (𝜇mole/L)	𝑃	Nitrate (µmole/L)	𝑃	Nitrite; (µmole/L)	𝑃
Gender	Group
Male	1 (negative control)	22.43±3.0	0.005	9.23±1.67	0.45	13.21±2.18	0.00
	3 (positive control)	50.71±7.54		13.03±4.58		37.68±4.04
Female	2 (negative control)	26.22±2.02	0.13	6.50±1.83	0.32	19.71±1.03	0.12
	4 (positive control)	41.68±9.17		10.20±3.07		31.48±6.83