CD47: A Cell Surface Glycoprotein Which Regulates Multiple Functions of Hematopoietic Cells in Health and Disease

<table>Interactions of CD47 in <i>cis</i> and <i>trans</i>. CD47 interacts in <i>cis</i> with integrins, in <i>trans</i> with SIRPs, and can also bind the soluble protein TSP-1. The figure summarizes intracellular signaling events associated with CD47 upon binding to its interaction partners.</table>

International Scholarly Research Notices

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Figure 1

Figure 1: CD47: A Cell Surface Glycoprotein Which Regulates Multiple Functions of Hematopoietic Cells in Health and Disease 