Review Article

Amiodarone-Induced Cirrhosis of Liver: What Predicts Mortality?

Table 3

Prognostic indicators of 5-month survival.

Hazard ratio95% Confidence interval

Age0.99(0.94–1.05) 0.80
Sex 0.90(0.34–2.37)0.83
Diabetes 0.40(0.05–3.08)0.32
HTN1.34(0.43–4.10)0.62
Hyperlipidemia1.09(0.29–4.03)0.90
CAD1.49(0.51–4.36)0.46
CHF1.74(0.52–5.80)0.36
>200 mg/ <200 mg Amiodarone dose given1.35(0.48–3.84)0.56
Latency period 1.12 (0.90–1.38) 0.33
Cumulative dose1.001(0.999–1.003)0.09
Prothrombin time 1.04 (0.97–1.11)0.36
Bilirubin (micromole/liter)0.998(0.99–1.00)0.45
AST1.003 (1.001–1.006)0.03
ALK P1.000(0.999–1.001)0.98
Albumin0.99(0.91–1.09)0.89
ALT1.002(0.999–1.005) 0.21
GGT 1.000(0.998–1.002)0.87

Not all studies had data on all the variables.