Frequent DNA Hypermethylation at the RASSF1A and APC Gene Loci in Prostate Cancer Patients of Pakistani Origin

Table 1

Clinical characteristics of prostate cancer and benign prostatic hyperplasia patients.

Clinical variable	Prostate cancer patients	BPH patients
Age (y)	67±7	66±4
Mean	67	66
Median	70	66.5
Range	55–78	53–78
Preoperative PSA (ng/mL)
Median	13	2.98
Range	1.2–487	0.65–65
TNM stage
Stage T1a	0 (0%)
Stage T1b	4 (15%)
Stage T1c	3 (11%)
Stage T2a	7 (26%)
Stage T2b	3 (11%)
Stage T2c	3 (11%)
Stage T3a	7 (30%)
Gleason score
5	2 (7%)
6	9 (33%)
7	6 (22%)
8	4 (16%)
9	6 (22%)
Lymph node involvement	2 (7%)
Seminal vesicle involvement	6 (22%)
Distant metastasis	4 (15%)
Total	27	24