Research Article

DLK1 Protein Expression during Mouse Development Provides New Insights into Its Function

Figure 7

DLK1 protein expression in the developing pancreas. ((a)–(d)) They show sections of ED10, -13, -16, and -18 pancreas, with ED10 strong DLK1 protein expression in the entire pancreas (arrow) and moderate positivity in the surrounding mesenchyme (arrowhead). By ED13, positivity is mainly confined to the distally growing epithelium of the developing pancreas (arrows) and the surrounding mesenchyme. On ED16, DLK1 protein expression becomes virtually restricted to the pancreatic mesenchyme (inset in (c); bar: 10 μm) and on ED18 the entire pancreas has become negative. (i) islet of Langerhans. Scale bar in (a) is applicable for ((b)–(d)).
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(a)
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(b)
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(c)
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(d)