Review Article
Risk of Cancer in Diabetes: The Effect of Metformin
Table 3
Role of AMPK in regulating energy balance at the whole body.
| Pancreas | Modulation of insulin secretion | Liver | Inhibition of gluconeogenesis Inhibition of cholesterol synthesis | Adipose tissue | Inhibition of lipolysis | Skeletal muscle | Increase glucose uptake Increase fatty acid oxidation | Hypothalamus | Increase food intake | Heart | Increase glucose uptake Increase fatty acid oxidation |
|
|
AMPK: adenosine monophosphate kinase.
|