Scientific Challenges and Implementation Barriers to Translation of Pharmacogenomics in Clinical Practice

<table class="table-group" id="tab2"><tr><td><table class="table"><tr><td class="thead-hr" colspan="2"><hr/></td></tr><tr class="thead"><td align="left">Issue</td><td align="left">Challenge</td></tr><tr><td class="thead-hr" colspan="2"><hr/></td></tr><tr><td align="left">Test performance</td><td align="left">Reasonable turnaround time for delivery of test result</td></tr><tr><td align="left">Interpretation of result</td><td align="left">Not a straightforward normal versus abnormal interpretation<br/>Education of clinicians is crucial to proper use</td></tr><tr><td align="left">Education of health professionals</td><td align="left">Variable time and content devoted to educating future clinicians within health professional schools<br/>Overwhelming information for most current practicing clinicians </td></tr><tr><td align="left">Cost reimbursement by payers</td><td align="left">Almost exclusively based on proof of cost-effectiveness </td></tr><tr><td align="left">Acceptance by clinicians </td><td align="left">Potential additional workload<br/>Potential legal liability<br/>Health disparity concern for patient</td></tr><tr><td align="left">Acceptance by patients</td><td align="left">Privacy and discrimination concern<br/>Health disparity concern<br/>Ownership of genetic information</td></tr><tr class="table-tr"><td colspan="2"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

Practical issues involved in clinical implementation of pharmacogenomic testing in healthcare system.

International Scholarly Research Notices

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Table 2

Table 2: Scientific Challenges and Implementation Barriers to Translation of Pharmacogenomics in Clinical Practice 