Soy Saponins Meditate the Progression of Colon Cancer in Rats by Inhibiting the Activity of β-Glucuronidase and the Number of Aberrant Crypt Foci but Not Cyclooxygenase-2 Activity

Figure 2

The pathological assessment performed by methylene blue staining in the ACFs of the colonic mucosa of rats^1,2. ¹ACFs: aberrant crypt foci. ²PS0: received saline and fed AIN93G diet; PS0.5: received saline and fed AIN93G diet containing 0.5% saponins; DSO: received 1,2-dimethylhydrazine (DMH) and fed AIN93G diet; DS0.5: received DMH and fed AIN93G diet containing 0.5% saponins; DS1: received DMH and fed AIN93G diet containing 1% saponins.