Soy Saponins Meditate the Progression of Colon Cancer in Rats by Inhibiting the Activity of β-Glucuronidase and the Number of Aberrant Crypt Foci but Not Cyclooxygenase-2 Activity

Table 2

The counts of small ACFs in rats^1,2.

	The incidence of ACFs^3	1AC	2AC	3AC	Small^4
PS0	0/4	ND^5	ND	ND	ND
PS0.5	0/4	ND	ND	ND	ND
DS0	6/6	10.16±1.22^a	9.00±1.46^a	5.83±0.70	25.00±1.89^a
DS0.5	6/6	5.67±0.59^ab	6.00±0.75^ab	3.83±0.41	15.50±0.54^b
DS1	6/6	2.83±0.39^b	1.83±0.50^b	3.00±0.63	7.67±1.32^c

1Data are expressed as mean ± SEM (𝑛=6).
²PS0: received saline and fed AIN93G diet; PS0.5: received saline and fed AIN93G diet containing 0.5% saponins; DS0: received 1,2-dimethylhydrazine (DMH) and fed AIN93G diet; DS0.5: received DMH and fed AIN93G diet containing 0.5% saponins; DS1: received DMH and fed AIN93G diet containing 1% saponins.
³The incidence of ACFs is the number of ACF rats/the number of total rats.
⁴Small ACFs: 1~3AC/ACF.
⁵ND: No detection.
^abcLetters in each column sharing the different superscripts are significantly different (𝑃<0.05).