Soy Saponins Meditate the Progression of Colon Cancer in Rats by Inhibiting the Activity of β-Glucuronidase and the Number of Aberrant Crypt Foci but Not Cyclooxygenase-2 Activity

Table 3

The counts of large ACFs in rats^1,2.

	The incidence of ACFs^3	4AC	5AC	6AC	Large^4
PS0	0/4	ND^5	ND	ND	ND
PS0.5	0/4	ND	ND	ND	ND
DS0	6/6	1.67±0.27	0.17±0.09	0.17±0.09	2.00±0.20^a
DS0.5	6/6	1.17±0.17	ND	ND	1.17±0.17^ab
DS1	6/6	0.17±0.09	0.17±0.09	ND	0.33±0.12^b

1Data are expressed as mean ± SEM (𝑛=6).
²PS0: received saline and fed AIN93G diet; PS0.5: received saline and fed AIN93G diet containing 0.5% saponins; DS0: received 1,2-dimethylhydrazine (DMH) and fed AIN93G diet; DS0.5: received DMH and fed AIN93G diet containing 0.5% saponins; DS1: received DMH and fed AIN93G diet containing 1% saponins.
³The incidence of ACFs is the number of ACF rats/the number of total rats.
⁴Large ACFs: >3AC/ACF.
⁵ND: No detection.
^abLetters in each column sharing the different superscripts are significantly different (𝑃<0.05).