Cell Proliferation (KI-67) Expression Is Associated with Poorer Prognosis in Nigerian Compared to British Breast Cancer Women

Table 3

Relationship between clinicopathological parameters in Nigerian and UK tumours expressing KI-67.

Variables	KI-67 positive expression
	Nigeria (%)	UK (%)	𝜒^2 value	P value
Age (years)
≤50	136 (62.4)	62 (37.8)	22.65	<0.001
>50	82 (37.6)	102 (62.2)
Menopausal
Pre	157 (72.0)	60 (36.8)	47.15	<0.001
Post	61 (28.0)	103 (63.2)
Sizes (cm)
≤2	18 (8.3)	73 (44.5)	67.79	<0.001
>2	200 (91.7)	91 (55.5)
Lymph node involvement
Negative	16 (7.3)	97 (59.1)	120.58	<0.001
Positive	202 (92.7)	67 (40.9)
Vascular invasion
Negative	51 (23.4)	86 (52.4)	34.32	<0.001
Positive	167 (76.6)	78 (47.6)
Tumour type
Typical medullary	3 (1.4)	1 (0.6)	43.10	<0.001
Atypical medullary	4 (1.8)	7 (4.3)
Tubular	1 (0.5)	0 (0.0)
Lobular	3 (1.4)	8 (4.9)
Ductal NST	189 (86.7)	105 (64.8)
Mucinous	4 (1.8)	0 (0.0)
Tubulolobular	0 (0.0)	7 (4.3)
Mixed NST	14 (6.4)	30 (18.5)
Others	0 (0.0)	2 (1.2)

NST: no special type. Others: metaplastic, spindle, and alveolar lobular histological type.