Clinical Study
Epidemiology and Prognosis of Paraneoplastic Syndromes in Hepatocellular Carcinoma
Table 2
Prognostic variables in HCC patients with and without paraneoplastic syndromes (PNS).
| Prognostic variable | With PNS () | Without PNS () | |
| Young age (≤40 years) | 13 (10.2%) | 28 (8.5%) | NS | AFP ≥ 12,000 g/L | 59 (46.5%) | 88 (26.7%) | <0.001 | Bilobar disease | 73 (57.5%) | 158 (47.9%) | NS | Multiple lesions | 92 (72.4%) | 216 (65.5%) | NS | Portal vein invasion | 64 (50.4%) | 141 (50.9%) | NS | Distant metastases | 28 (22.0%) | 59 (17.9%) | NS | TNM stage (I&II/III&IV) | 25/102 (19.7%/80.3%) | 110/220 (33.3%/66.7%) | 0.017 | Child-Pugh A/B/C | 57/53/17 (44.9%/41.7%/13.4%) | 146/135/49 (44.2%/40.9%/14.8%) | NS |
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PNS: paraneoplastic syndromes; NS: not statistically significant ().
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