Research Article

Characterization of the Visceral Antinociceptive Effect of Glial Glutamate Transporter GLT-1 Upregulation by Ceftriaxone

Figure 3

Mice treated with vehicle or CTX (100 mg/kg) for seven days were observed for the amount of time spent licking the abdominal area for 1 hr after receiving intravesicular (ivc) vehicle or acrolein (0.4 mM). The data show a significantly enhanced time spent licking in animals that received 1 wk VEH + ivc ACRO, compared to the control group (1 wk VEH + ivc VEH; * ). This enhanced nociceptive response was attenuated in cohorts receiving 1 wk CTX + ivc ACRO treatment.
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