Characterization of the Visceral Antinociceptive Effect of Glial Glutamate Transporter GLT-1 Upregulation by Ceftriaxone
Figure 5
(a)-(b) Total and membrane-associated GluR1 is increased after 1-week cyclophosphamide treatment. Enhanced GluR1 membrane trafficking is mitigated after concomitant 1 wk CTX and cyclophosphamide treatment. (a) Western blot comparing Total, cytosolic, and membrane GruR1 expression. (b) Representative western blot densitometry shows a 20% increase in total GluR1 expression in 1 wk VEH + CYP and a 22% increase in the membrane compared to control cohorts 1 wk VEH + VEH (*).
