Review Article

Retrospective Study of Seven Cases with Acute Fatty Liver of Pregnancy

Table 6

The overall summary of the 126 cases of AFLP.

Particulars
cases

cases
value test

Maternal age (years)26 years 
(Range, 21–32)
27 years 
(Range, 21–37)
Mean gestational age (weeks)36 weeks 
(Range, 32–38)
36 weeks 
(Range, 28–38)
Primigravida 85.7 (6/7)74.6 (94/126)0.8370.045
Multigravida14.2 (1/7)25.4 (32/126)
Mode of delivery
 Cesarean section71.4 (5/7)86.5 (109/126)0.5790.308
 Vaginal delivery28.5 (2/7)13.4 (17/126)
Complications
 Hypoglycemia57.1 (4/7)41.2 (52/126)0.6640.189
 Acute renal insufficiency100 (7/7)50.7 (64/126)0.0314.626
 ARDS42.8 (3/7)40.4 (51/126)10
 Coagulopathy57.1 (4/7)78.5 (99/126)0.3920.732
 Encephalopathy42.8 (3/7)46 (58/126)10
 MODS57.1 (4/7)30.1 (38/126)0.2811.16
Outcomes
 Maternal death
  Cesarean section20 (1/5)12.8 (14/109)0.513
  Vaginal delivery0 (0/2)35.2 (6/17)1
Perinatal/postnatal death
 Cesarean section28.5 (2/7)8.9 (12/134)0.144
 Vaginal delivery66.6 (2/3)28 (7/25)0.234

ARDS: Acute respiratory distress syndrome; MODS: Multiple organ dysfunction syndrome.