Utility of Nuclear Morphometry in Predicting Grades of Diffusely Infiltrating Gliomas
Table 1
Mean values of age and nuclear parameters of the two study and the control groups with their standard deviation and range. values between each pair of group for all the parameters.
Parameters (unit) ± SD (min–max)
Group (no. of cases)
value
CG (10)
LGG (14)
HGG (16)
(CG versus LGG)
(CG versus HGG)
(LGG versus HGG)
Age (year) ± SD (min–max)
46.3 ± 3.5 (40–53)
39.1 ± 14.1 (9–62)
54.6 ± 16.8 (27–79)
0.1335*
0.1397*
0.0116
MAJX (m) ± SD (min–max)
6.96 ± 0.59 (6.23–8.07)
9.41 ± 0.81 (7.51–10.30)
10.73 ± 1.33 (8.90–12.87)
<0.0001
<0.0001
0.0032
MINX (m) ± SD (min–max)
4.62 ± 0.35 (4.18–5.30)
6.34 ± 0.70 (4.98–7.56)
7.11 ± 0.94 (4.66–8.70)
<0.0001
<0.0001
0.0184
NA (m2) ± SD (min–max)
23.44 ± 4.01 (19.42–30.33)
42.62 ± 7.26 (27.15–55.23)
55.22 ± 13.48 (30.26–76.90)
<0.0001
<0.0001
0.0042
NP (m) ± SD (min–max)
21.54 ± 2.11 (18.84–25.33)
29.79 ± 2.80 (23.34–32.74)
34.24 ± 4.49 (28.92–41.91)
<0.0001
<0.0001
0.0034
NR (%) ± SD (min–max)
65.55 ± 4.34 (59.85–73.48)
61.53 ± 5.42 (48.99–70.43)
59.78 ± 5.80 (48.94–70.40)
0.0659*
0.0125
0.4011*
ND (per mm2) ± SD (min–max)
1107 ± 138 (849–1282)
3232 ± 1596 (1456–5633)
4350 ± 1089 (1941–6360)
<0.0004
<0.0001
0.0314
%TNA
2.32 ± 0.54 (1.65–3.33)
9.98 ± 4.34 (3.63–17.35)
15.88 ± 7.48 (6.64–35.33)
<0.0001
<0.0001
0.0151
CG: control group; LGG: low-grade gliomas; HGG: high-grade gliomas; min: minimum; max: maximum; (X versus Y): value between X group versus Y group by Student's unpaired -test; *: difference is not significant.
