Increased Frequency of Antigen-Specific Polyfunctional T Cells in Tuberculosis Patients

Figure 3

Enumeration of antigen-specific dual cytokine-secreting T cells in HHC and TB patients. Box and Whisker plots show range, interquartile range, and median of antigen-specific CD4⁺IFN-γ ⁺IL-2⁺ T cell (a) and CD8⁺IFN-γ ⁺IL-2⁺ T cell (b) in HHC and TB patients. The frequency of IFN-γ ⁺IL-2⁺ T cell subset did not differ between HHC and TB patients. The difference between HHC and TB was calculated by Mann-Whitney 𝑈 test. TB: tuberculosis patients; HHCs: healthy household contacts.

(a)

(b)