Estrogen Signaling and the Aging Brain: Context-Dependent Considerations for Postmenopausal Hormone Therapy
Figure 1
Representative image of domains within human and rat ERβ splice variants. Human ERβ splice variants (a) contain truncations and changes in amino acid sequence in the C-terminus E and F domains. Rat ERβ splice variants (b) contain an 18-amino-acid insert in the LBD/E domain and/or exon 3/4 exclusions in the DNA-binding domain.