Research Article
Genotoxicological Evaluation of NUTRALYS Pea Protein Isolate
Table 3
Summary of in vitro chromosomal aberrations in human lymphocytes.
| Concentration
(g/mL) | Total no. of metaphases scored | 3 h with S9 (10%) | 3 h without S9 | Continuous without S9 | | % Numerical aberrations | % Structural aberrations (exclusive to gaps)* | % Numerical aberrations | % Structural aberrations (exclusive to gaps)* | % Numerical aberrations | % Structural aberrations (exclusive to gaps)* |
| | Solvent control (sterile millipore water 50 L/5 mL culture) | 200 | 0 | 2.0 | 0 | 5.0 | 0 | 2.5 | | 125 | 200 | 0 | 1.5 | 0 | 2.5 | 0 | 2.5 | | 250 | 200 | 0 | 1.0 | 0 | 3.0 | 0 | 2.5 | | 500 | 200 | 0 | 2.5 | 0 | 5.0 | 0 | 2.5 | | Positive control# | 50 | 0 | 44.0 | 0 | 96.0 | 0 | 70.0 |
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20 g/mL cyclophosphamide (with S9); 0.8 g/mL mitomycin C (without S9).
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