Emptying of Intracellular Calcium Pool and Oxidative Stress Imbalance Are Associated with the Glyphosate-Induced Proliferation in Human Skin Keratinocytes HaCaT Cells
Figure 1
(a) Proliferation effects of glyphosate on HaCaT cells. Cells were exposed to glyphosate (0.01–1 mM) and positive control, and TPA (10 nM) for 24, 48, and 72 h. (b) Inhibition of glyphosate (0.1 mM) induced cell proliferation after 72 h by a prior treatment of NAC (10 mM and 20 mM). OD values from three separate experiments are shown as mean ± SD. *Increase over vehicle control cells (); **decrease over glyphosate alone treated cells ().
