Microemulsion: New Insights into the Ocular Drug Delivery

Table 5

List of studied physicochemical parameters of various reported ocular MEs.

Authors	Drug	Physicochemical properties (mean ± SD)
		pH	Average diameter (nm)	Refractive index	Surface tension; (mN/m)	Viscosity; (mPa·s)
Gasco et al., 1989 [43]	Timolol maleate	—	15	—	—	24.8±0.7
Haße and Keipert, 1997 [45]	Pilocarpine nitrate	5.5–6.0	25–45	1.37–1.38	31-32	7.0–9.0
Fialho and da Silva-Cunha, 2004 [24]	Dexamethasone	6.99±0.02	50.85±1.24; (𝑛=6)	1.38±0.01	27.79±0.01	40.27±0.98
Lv et al., 2006 [25]	Chloramphenicol	—	53–59.5	—	—	—
Chan et al., 2007 [47]	Pilocarpine HCl	—	<100	—	34±1.6	167