Formulation Development and Evaluation of Drug Release Kinetics from Colon-Targeted Ibuprofen Tablets Based on Eudragit RL 100-Chitosan Interpolyelectrolyte Complexes

Figure 2

The various cumulative % drug release (𝐷) and the time of release (𝑇) at media pH of 1.2, 6.8, and 7.4, respectively. CS : EL (1 : 1) = tablets coated with IPEC containing 50% chitosan and 50% Eudragit RL 100. CS : EL (2 : 3) = tablets coated with IPEC containing 40% chitosan and 60% Eudragit RL 100. CS : EL (3 : 2) = tablets coated with IPEC containing 60% chitosan and 40% Eudragit RL 100. EL = control tablets coated with IPEC containing only Eudragit RL 100.