Evaluation of the Benefit of Routine Intraoperative Frozen Section Analysis of Sentinel Lymph Nodes in Breast Cancer

Table 4

Results of frozen section analysis of sentinel lymph node biopsy in the literature.

Reference	Year	𝑁	SNB+ (%)	SNB+/FS+	SNB+/FS−	FNR (%)
Wada [7]	2004	569	159 (28%)	133 (83.6%)	26	16.3%
Arora et al. [5]	2008	327	108 (33%)	78 (72.2%)	30	27.8%
McLaughlin et al. [8]	2008	931	306 (32.8%)	170 (55.6%)	136	44.4%
van de Vrande et al. [3]	2009	615	176 (28.6%)	126 (71.6%)	50	28.4%
Ali et al. [9]	2008	94	30 (33.3%)	23 (76.7%)	7	23.3%
Chan et al. [10]	2008	5298	1845 (34.8%)	1124 (60.9%)	721	39.1%
This study	—	628	179 (28.5%)	78 (43.6%)	101	56.4%

𝑁: number of patients, SNB+: sentinel node biopsy with positive result, FS+: frozen section with positive result, FS−: frozen section with negative result, FNR: false negative rate.