A Practical Update of Surgical Management of Merkel Cell Carcinoma of the Skin

Table 8

Indications for adjuvant radiotherapy; see text for more liberal indications.

(1) Primary tumor size > 2 cm
(2) Positive resection margins or tumors that closely approximate the surgical margin
(3) Lymphovascular invasion in the primary tumor
(4) Extracapsular extension of tumor outside nodes
(5) Documented regional lymph node involvement or when regional lymph nodes were not pathologically staged