About this Journal Submit a Manuscript Table of Contents
ISRN Neurology
Volume 2013 (2013), Article ID 867575, 6 pages
http://dx.doi.org/10.1155/2013/867575
Clinical Study

Quantifying Gait Impairment Using an Instrumented Treadmill in People with Multiple Sclerosis

1Multiple Sclerosis Center, Sheba Medical Center, Tel Hashomer, Israel
2Institute of Motor Functions, Sheba Medical Center, Tel Hashomer, Israel
3Sackler Faculty of Medicine, Tel-Aviv University, Israel

Received 26 May 2013; Accepted 13 June 2013

Academic Editors: D. E. Bulman, A. Mamelak, A. K. Petridis, and D. Schiffer

Copyright © 2013 Alon Kalron et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. L. J. White and R. H. Dressendorfer, “Exercise and multiple sclerosis,” Sports Medicine, vol. 34, no. 15, pp. 1077–1100, 2004. View at Publisher · View at Google Scholar · View at Scopus
  2. National Multiple Sclerosis Society, “Epidemiology of MS,” 2009, http://www.NMSS.org.
  3. J. H. Noseworthy, C. Lucchinetti, M. Rodriguez, and B. G. Weinshenker, “Multiple sclerosis,” The New England Journal of Medicine, vol. 343, no. 13, pp. 938–952, 2000. View at Publisher · View at Google Scholar · View at Scopus
  4. O. R. Pearson, M. E. Busse, R. W. M. Van Deursen, and C. M. Wiles, “Quantification of walking mobility in neurological disorders,” Quarterly Journal of Medicine, vol. 97, no. 8, pp. 463–475, 2004. View at Publisher · View at Google Scholar · View at Scopus
  5. J. C. Hobart, D. L. Lamping, R. Fitzpatrick, A. Riazi, and A. Thompson, “The multiple sclerosis impact scale (MSIS-29) a new patient-based outcome measure,” Brain, vol. 124, no. 5, pp. 962–973, 2001. View at Scopus
  6. A. Kalron, A. Achiron, and Z. Dvir, “Muscular and gait abnormalities in persons with early onset multiple sclerosis,” Journal of Neurologic Physical Therapy, vol. 35, no. 4, pp. 164–169, 2011. View at Publisher · View at Google Scholar · View at Scopus
  7. H. Lassmann, “The pathology of multiple sclerosis and its evolution,” Philosophical Transactions of the Royal Society B, vol. 354, no. 1390, pp. 1635–1640, 1999. View at Scopus
  8. B. G. Weinshenker, B. Bass, G. P. A. Rice et al., “The natural history of multiple sclerosis: a geographically based study. I. Clinical course and disability,” Brain, vol. 112, part 1, pp. 133–146, 1989. View at Scopus
  9. U. Givon, G. Zeilig, and A. Achiron, “Gait analysis in multiple sclerosis: characterization of temporal-spatial parameters using GAITRite functional ambulation system,” Gait and Posture, vol. 29, no. 1, pp. 138–142, 2009. View at Publisher · View at Google Scholar · View at Scopus
  10. J. J. Sosnoff, B. M. Sandroff, and R. W. Motl, “Quantifying gait abnormalities in persons with multiple sclerosis with minimal disability,” Gait & Posture, vol. 36, no. 1, pp. 154–156, 2012.
  11. O. Faude, L. Donath, R. Roth, L. Fricker, and L. Zahner, “Reliability of gait parameters during treadmill walking in community-dwelling healthy seniors,” Gait & Posture, vol. 36, no. 3, pp. 444–448, 2012.
  12. M. Zwecker, “Assessing special features of impaired gait after acquired brain injury with an instrumented treadmill,” National Institute of Health Clinical Trials Registry, 2012, http://clinicaltrials.gov/show/NCT01413321.
  13. C. H. Polman, S. C. Reingold, B. Banwell et al., “Diagnostic criteria for multiple sclerosis: 2010 revisions to the McDonald criteria,” Annals of Neurology, vol. 69, no. 2, pp. 292–302, 2011. View at Publisher · View at Google Scholar · View at Scopus
  14. R. W. Motl, B. M. Sandroff, Y. Suh, and J. J. Sosnoff, “Energy cost of walking and its association with gait parameters, daily activity, and fatigue in persons with mild multiple sclerosis,” Neurorehabilitation and Neural Repair, vol. 26, no. 8, pp. 1015–1021, 2012.
  15. K. Parvataneni, L. Ploeg, S. J. Olney, and B. Brouwer, “Kinematic, kinetic and metabolic parameters of treadmill versus overground walking in healthy older adults,” Clinical Biomechanics, vol. 24, no. 1, pp. 95–100, 2009. View at Publisher · View at Google Scholar · View at Scopus
  16. T. Warabi, M. Kato, K. Kiriyama, T. Yoshida, and N. Kobayashi, “Treadmill walking and overground walking of human subjects compared by recording sole-floor reaction force,” Neuroscience Research, vol. 53, no. 3, pp. 343–348, 2005. View at Publisher · View at Google Scholar · View at Scopus
  17. K. N. Kirkwood, B. de Souza Moriera, M. L. Vallone, S. A. Mingoti, R. C. Dias, and R. F. Sampaio, “Step length appears to be a strong discriminant gait parameter for elderly females highly concerned about falls: a cross-sectional observational study,” Physiotherapy, vol. 97, no. 2, pp. 126–131, 2011.
  18. U. Puh and G. Baer, “A comparison of treadmill walking and overground walking in independently ambulant stroke patients: a pilot study,” Disability and Rehabilitation, vol. 31, no. 3, pp. 202–210, 2009. View at Publisher · View at Google Scholar · View at Scopus
  19. M. J. Socie, B. M. Sandroff, J. H. Pula, E. T. Hsiao-Wecksler, R. W. Motl, and J. J. Sosnoff, “Footfall placement variability and falls in multiple sclerosis,” Annals of Biomedical Engineering. In press.
  20. M. Flegel, K. Knox, and D. Nickel, “Step-length variability in minimally disabled women with multiple sclerosis or clinically isolated syndrome,” International Journal of MS Care, vol. 14, no. 1, pp. 26–30, 2012.
  21. M. L. Callisaya, L. Blizzard, M. D. Schmidt et al., “Gait, gait variability and the risk of multiple incident falls in older people: a population-based study,” Age and Ageing, vol. 40, no. 4, Article ID afr055, pp. 481–487, 2011. View at Publisher · View at Google Scholar · View at Scopus
  22. R. W. Motl, Y. Suh, D. Dlugonski et al., “Oxygen cost of treadmill and over-ground walking in mildly disabled persons with multiple sclerosis,” Neurological Sciences, vol. 32, no. 2, pp. 255–262, 2011. View at Publisher · View at Google Scholar · View at Scopus
  23. P. Thoumie, D. Lamotte, S. Cantalloube, M. Faucher, and G. Amarenco, “Motor determinants of gait in 100 ambulatory patients with multiple sclerosis,” Multiple Sclerosis, vol. 11, no. 4, pp. 485–491, 2005. View at Publisher · View at Google Scholar · View at Scopus
  24. J. J. Sosnoff, E. Gappmaier, A. Frame, and R. W. Motl, “Influence of spasticity on mobility and balance in persons with multiple sclerosis,” Journal of Neurologic Physical Therapy, vol. 35, no. 3, pp. 129–132, 2011. View at Publisher · View at Google Scholar · View at Scopus
  25. J. M. Huisinga, M. L. Filipi, K. K. Schmid, and N. Stergiou, “Is there a relationship between fatigue questionnaires and gait mechanics in persons with multiple sclerosis?” Archives of Physical Medicine and Rehabilitation, vol. 92, no. 10, pp. 1594–1601, 2011. View at Publisher · View at Google Scholar · View at Scopus
  26. R. Schniepp, M. Wuehr, M. Neuhaeusser et al., “Locomotion speed determines gait variability in cerebellar ataxia and vestibular failure,” Movement Disorders, vol. 27, no. 1, pp. 125–131, 2012. View at Publisher · View at Google Scholar · View at Scopus
  27. J. J. Sosnoff, M. J. Socie, M. K. Boes et al., “Mobility, balance and falls in persons with multiple sclerosis,” PLoS ONE, vol. 6, no. 11, Article ID e28021, 2011. View at Publisher · View at Google Scholar · View at Scopus
  28. A. Kalron, Z. Dvir, and A. Achiron, “Walking while talking-Difficulties incurred during the initial stages of multiple sclerosis disease process,” Gait and Posture, vol. 32, no. 3, pp. 332–335, 2010. View at Publisher · View at Google Scholar · View at Scopus