Clinical Study

Quantifying Gait Impairment Using an Instrumented Treadmill in People with Multiple Sclerosis

Table 2

Descriptive statistics of the spatiotemporal gait parameters.

VariableMean (S.D.)Mean difference (95% CI) value
MS participants ( )Healthy subjects ( )

Velocity (km/h)2.2 (1.0)3.5 (0.7)−1.3 (−1.7, −0.9)<0.001
Cadence (steps/min)94.4 (18.5)101.1 (11.3)−6.7 (−12.7, −0.7)0.03
Step time R (sec)0.66 (0.15)0.60 (0.07)0.06 (0.02, 0.1)0.007
Step time L (sec)0.67 (0.15)0.60 (0.07)0.07 (0.02, 0.1)0.002
Step length R (cm)37.7 (14.8)57.1 (8.7)−19.4 (−24.0, −14.7)<0.001
Step length L (cm)37.4 (14.5)57.6 (8.6)−20.2 (−24.9, −15.6)<0.001
Stance R (% GC)69.4 (5.4)64.4 (2.0)5.0 (3.6, 6.4)<0.001
Stance L (% GC)69.3 (5.6)64.2 (2.1)5.1 (3.7, 6.5)<0.001
Single support R (% GC)30.6 (5.6)35.6 (2.1)−5.0 (−6.6, −3.7)<0.001
Single support L (% GC)30.6 (5.5)35.6 (2.0)−5.0 (−6.5, −3.6)<0.001
Double support (% GC)38.8 (10.5)28.6 (4.0)10.2 (7.4, 12.9)<0.001
Stride time (sec)1.33 (0.29)1.20 (0.14)0.13 (0.04, 0.2)0.004
Stride length (cm)75.1 (29.0)114.7 (17.1)−39.6 (−51.7, −27.5)<0.001
Base of support (cm)13.8 (4.1)11.0 (3.0)2.8 (1.1, 4.6)<0.001

Statistics obtained from the butterfly diagram
A-P variability (mm)8.5 (5.9)3.4 (1.3)5.1 (3.7, 6.4)<0.001
Lateral symmetry (mm)8.6 (7.9)3.3 (2.5)5.3 (3.4, 7.3)0.001
Lateral variability (mm)18.3 (13.6)7.6 (8.1)10.7 (6.4, 15.1)<0.001