Disrupted Central Inhibition after Transcranial Magnetic Stimulation of Motor Cortex in Schizophrenia with Long-Term Antipsychotic Treatment
Table 2
The results of the TMS measurements and significant (: probability) differences in the subjects with schizophrenia compared to controls.
Group
Controls
Total
CA
AA
Number
9
11
6
5
Site of stim.
ADM
ADM
ADM
ADM
(sd)
(sd)
(sd)
(sd)
Nondominant body side
MCT
21.5 (1.4)
21.2 (1.8)
20.7 (1.8)
21.8 (1.6)
CMCT
6.6 (1.2)
6.5 (1.5)
6.1 (1.3)
7.0 (1.6)
CSP
First duration
104.2 (59.2)
101.8 (5.7)
72.0 (57.2)
137.60 (85.6)
Total duration
83.1 (57.8)
166.9 (76.7)
97.3 (81.6)
169.4 (102.0)
Total number
1.2 (0.4)
2.1 (0.9)
2.17 (1.17)
2.0 (0.7)
CSP latency
56.0 (7.6)
53.2 (6.2)
54.5 (6.6)
51.6 (6.1)
Site of stim.
TA
TA
TA
TA
MCT
28.9 (1.5)
29.9 (2.3)
29.0 (2.4)
31.1 (1.6)
CMCT
11.7 (1.5)
12.8 (1.6)
12.6 (1.2)
12.9 (1.5)
CSP
First duration
60.3 (47.8)
88.8 (67.2)
48.3 (10.6)
137.4 (75.7)
Total duration
73.9 (58.0)
138.7 (101.8)
48.3 (10.6)
179.4 (88.6)
Total number
1.3 (0.5)
1.4 (0.5)
1.0 (0.0)
1.8 (0.5)
CSP latency
63.8 (10.8)
67.3 (7.3)
64.8 (8.8)
70.2 (4.1)
Dominant body side
MCT
21.8 (1.6)
21.4 (1.7)
20.9 (1.9)
21.9 (1.4)
CMCT
6.9 (1.5)
6.5 (1.3)
6.0 (1.5)
7.0 (1.1)
CSP
First duration
83.1 (57.8)
140.1 (79.7)
137.2 (91.6)
143.6 (73.3)
Total duration
106.0 (60.6)
130.1 (94.4)
166.8 (79.4)
167.0 (82.8)
Total number
1.0 (0.0)
1.8 (0.6)
2.0 (0.6)
1.6 (0.6)
CSP latency
56.6 (7.0)
54.9 (9.4)
56.2 (10.7)
53.4 (8.6)
Site of stim.
TA
TA
TA
TA
MCT
29.5 (2.1)
29.0 (4.2)
27.5 (5.0)
30.9 (2.1)
CMCT
12.2 (1.5)
12.0 (3.7)
11.0 (4.9)
13.2 (1.3)
CSP
First duration
71.2 (51.7)
96.3 (59.0)
73.2 (37.5)
124.0 (72.1)
Total duration
67.1 (53.3)
107.9 (88.8)
87.8 (59.3)
199.8 (113.9)
Total number
1.1 (0.3)
1.7 (0.6)
1.3 (0.5)
2.2 (0.5)
CSP latency
68.0 (8.0)
69.1 (8.8)
67.0 (9.5)
71.6 (8.2)
Mean: ; sd: standard deviation; MCT: motor conduction time; CMCT: central motor conduction time; CSP: central silent period; ADM: abductor digiti minimi and TA: tibialis anterior muscles; total: all subjects with schizophrenia; CA: users of conventional antipsychotics; AA: users of atypical antipsychotics; time values are means in milliseconds, : number of subjects.
