Research Article

A Validated Stability-Indicating RP-HPLC Method for the Simultaneous Determination of Tenofovir, Emtricitabine, and a Efavirenz and Statistical Approach to Determine the Effect of Variables

Table 4

Results of precision studies by the proposed method ( ).

DrugAmount added ( g mL−1)Amount found (μg mL−1) ± SD; % RSD
IntradayInterday

FTC200199.94 ± 0.34; 0.19198.84 ± 0.53; 0.27
TDF245247.54 ± 0.19; 0.07244.51 ± 0.62; 0.25
EFV600603.06 ± 0.78; 0.13595.98 ± 1.66; 0.28