Research Article

Development and Validation of a Stability Indicating RP-UPLC Method for Analysis of Imipramine Hydrochloride in Pharmaceuticals

Table 10

Results of recovery study by standard addition method.

Tablet studiedIMH in tablet, g/mLPure IMH added, g/mLTotal found, g/mLPure IMH recovered* (% IMH ± SD)

Impramine
0.50.50.99899.84 ± 0.09
0.51.01.502100.22 ± 0.11
0.51.51.99699.79 ± 0.25

Depranil0.50.51.004100.89 ± 0.04
0.51.01.49599.54 ± 0.12
0.51.51.99599.68 ± 0.23

 *Mean value of five determinations.