Research Article
Development and Validation of a Stability Indicating RP-UPLC Method for Analysis of Imipramine Hydrochloride in Pharmaceuticals
Table 10
Results of recovery study by standard addition method.
| Tablet studied | IMH in tablet, g/mL | Pure IMH added, g/mL | Total found, g/mL | Pure IMH recovered* (% IMH ± SD) |
| Impramine
| 0.5 | 0.5 | 0.998 | 99.84 ± 0.09 | 0.5 | 1.0 | 1.502 | 100.22 ± 0.11 | 0.5 | 1.5 | 1.996 | 99.79 ± 0.25 |
| Depranil | 0.5 | 0.5 | 1.004 | 100.89 ± 0.04 | 0.5 | 1.0 | 1.495 | 99.54 ± 0.12 | 0.5 | 1.5 | 1.995 | 99.68 ± 0.23 |
|
|
*Mean value of five determinations.
|