Targeted Drug Delivery to Endothelial Adhesion Molecules

Figure 5

Cell adhesion molecule (CAM)-mediated approach to the delivery of diagnostic and/or therapeutic nanoparticles to injured vascular endothelium in early inflammation. (a) Leukocyte adhesion and transmigration mediated by CAMs resulting in propagation of inflammation; (b) imaging or therapy of vascular sites of early inflammation via delivery of CAM-targeted nanoparticles. From Chacko et al. [45].