Gene Expression Profile Analysis of T1 and T2 Breast Cancer Reveals Different Activation Pathways

Table 4

Univariate comparison of predictors.

Covariate	HR [95% CI]	𝑃	PVE	Deviance	𝐶
T-size signature
(Overall effect)		4.30𝐸−07	2.76𝐸−02	25.55	0.58
T2-like (versus T1-like)	1.92 [1.48–2.48]	7.22𝐸−07
Tumor size
(Overall effect)		5.63𝐸−08	3.62𝐸−02	33.38	0.60
2 (versus 1)	1.95 [1.50–2.55]	7.83𝐸−07
3 (versus 1)	3.39 [1.96–5.88]	1.37𝐸−05
Node
(Overall effect)		2.40𝐸−06	2.46𝐸−02	22.24	0.58
+ (versus −)	1.89 [1.46–2.45]	1.35𝐸−06
ER
(Overall effect)		2.07𝐸−02	5.85𝐸−03	5.35	0.54
+ (versus −)	0.72 [0.55–0.94]	1.78𝐸−02
Histological grade
(Overall effect)		2.45𝐸−04	2.11𝐸−02	16.63	0.60
2 (versus 1)	1.78 [1.15–2.77]	1.04𝐸−02
3 (versus 1)	2.37 [1.52–3.69]	1.78𝐸−02